Short Course Program

Sunday 9 November 8.00-12.00 (4 hours)

Cost Estimation and Assessing Financial (Budget) Impact of New HealthCare Technologies Girona Room (-2 Level)

Faculty: Josephine Mauskopf PhD, Division Director, Global Health Economics, RTI Health Solutions, RTI International, RTP, NC, USA.; C. Daniel Mullins PhD, Professor, University of Maryland, School of Pharmacy, Baltimore, MD, USA

Course Description: This course will describe techniques in pharmacoeconomics that focus on cost. This will include methods to determine the cost-of-illness of a health condition using a “top-down” or “bottom-up” approach. Participants will also learn how to estimate the impact of new health care technologies on disease-specific costs from different decision-maker perspectives. Actuarial methods using straight-line projections and nonlinear trends will be described. Both static and dynamic methods for estimating the budget impact of adding a new drug to a health plan formulary will also be presented. This course is designed for those with some experience with pharmacoeconomic analysis.

Evidence-Based Health Care Reimbursement Systems in Europe - NICE and Beyond
Mallorca Room (-1 Level)

Faculty: Christian Gericke, MD, MSc, DTMH  Dept of Health Care Management, Technische Universität Berlin, Berlin, Germany

Course description: In this course, reimbursement systems for pharmaceutical products in Europe will be discussed. For all health care systems, the amount of resources to devote to health care is limited. An overview of main health care funding and resource allocation mechanisms for different types of services - hospitals, office-based physicians, and drugs - is given. Recent pharmaceutical spending patterns and trends in major European Union countries will be discussed taking account of the wider policy context. A range of cost-containment measures for pharmaceuticals will be presented, with a focus on pharmaceutical pricing strategies. The varying importance of pharmacoeconomics in pharmaceutical reimbursement within the EU will be discussed. Participants will have the possibility to apply the taught course contents in country case studies. This course is designed for those with little experience with European health care systems and pharmaceutical pricing and reimbursement.

Value/Valuation in Measuring Outcomes (Preference-Based Techniques)
Tibidabo Room (Mezzanine Level)

Faculty: Jan Busschbach PhD, Department of Medical Psychology, Erasmus MC, Rotterdam, Psychotherapeutic Centre ‘De Viersprong’, Rotterdam, The Netherlands

Course Description: This course offers a unique combination of theory and practice that examines the explicit valuations systems of generic instruments (including HUI, EQ-5D and SF-6D) as well as those implicit in widely used condition-specific instruments (including FACT-L, QLQC-30 and HADS). Examples from the published literature will be discussed using a critical review framework designed to test the status of such value systems. Practical experience of the principal preference-based techniques used in valuing health outcomes, such as willingness-to-pay, standard gamble, and time trade-off will be offered as an integral part of the course. The course is designed for those with at least an intermediate level experience of quality of life issues and practice.


Advanced Pharmacoeconomic Modeling Menorca Room (-1 Level)

Uwe Siebert MPh, MSc
, Harvard School of Public Health, Harvard Center for Risk Analysis, Boston, MA, USA; Gaby Sroczynski, MPH, Decision Scientist, Harvard Center for Risk Analysis, Harvard School of Public Health, Boston, USA

Course Description: This course will present an in-depth discussion of advanced pharmacoeconomic modeling techniques such as Monte Carlo analysis, Markov modeling, and probabilistic sensitivity analysis. This course is designed for those with experience with modeling techniques.

Meta-Analysis and Systematic Literature Review - Introduction
Roses Room (-2 Level)

Faculty: Maite Artes MSc, General Manager, ADELPHI TARGIS, Barcelona, Spain; Mateu Serra-Prat MD, MPH, Head of the Research Unit, Consorci Sanitari del Maresme CSdM, Barcelona, Spain

Course Description: Meta-analysis may be defined as the statistical analysis of data from multiple studies for the purpose of synthesizing and summarizing results, as well as for quantitatively evaluating sources of heterogeneity and bias. A systematic literature review often includes meta-analysis and involves an explicit, detailed description of how a review was conducted. This short course highlights and expounds upon four key areas: 1) impetus for meta-analysis and systematic reviews; 2) basic steps to perform a quantitative systematic review; 3) statistical methods of combining data; and 4) appraisal and use of meta-analytic reports. The material is motivated via applications in pharmacoeconomics, outcomes research, and clinical studies from the published literature and hypothetical examples. Interactive exercises are part of the course. This course is designed for those with little experience


The Analysis and Interpretation of Quality of Life and Patient Reported Outcomes

Faculty: Linda Abetz MA, Research Director, Mapi Values, Bollington, UK; Bruce Crawford MA, MPH, Project Director, Mapi Values, Boston, MA, USA

Course Description: This course is designed to provide a range of methods that may help to solve common problems encountered with Patient Reported Outcomes.  These include an overview of psychometric validation methods (including a brief overview of Rasch analysis), missing data analysis techniques, and a variety of methods to assess minimally clinically important differences.  Specific examples will be used throughout the course and participants will be asked to complete a short exercise. This course is designed for individuals with little experience with quality-of-life studies.

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