Short Courses - Sunday, 5 September 2010
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8:00am - 12:00pm MORNING COURSES
Introduction to Modeling
Faculty: Shu-Chuen Li PhD, MS, MBA, Professor, Chair & Head, Discipline of Pharmacy & Experimental Pharmacology, School of Biomedical Sciences, University of Newcastle, Callaghan, NSW, Australia
Course Description: This course will present pharmacoeconomic modeling techniques such as decision analytic modeling, Markov modeling, discrete event models, and other modeling techniques and their appropriate usages including a review of the ”ISPOR Principles of Good Practice for Decision Analytic Modeling in Health Care Evaluation”. Examples will be presented using Microsoft Excel, supplemented with add on simulation software. This course will cover the practical steps involved in the selection of models and options in modeling of data inputs. This introductory/intermediate course requires basic understanding of decision analysis.
S. Li
  Introduction to Pharmacoeconomics
Faculty: David Bruce Matchar MD, Professor and Program Director for Health Service & Systems Research, Duke-National University of Singapore (Duke-NUS) Graduate Medical School, Singapore, Singapore; Usa Chaikledkaew PhD, Assistant Professor, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand
Course Description:
This course is designed to teach clinicians and researchers how to incorporate pharmacoeconomics into study design and data analysis. Participants will learn how to collect and calculate the costs of different health care treatments, determine the economic impact of clinical outcomes, and how to identify, track and assign costs to different types of health care resources used. Different assessment methods including cost-effectiveness, cost-minimization, cost of illness, cost-utility and cost-benefit analysis will be discussed. The applications of pharmacoeconomics will be covered and illustrated by practical examples. This introductory course is designed to assist decision making for health care workers.
D. Matchar  
U. Chaikledkaew
  Retrospective Data Analysis
Faculty: Jeff J. Guo B. Pharm, PhD, Associate Professor of Pharmacoeconomics & Pharmacoepidemiology, James L. Winkle College of Pharmacy, University of Cincinnati Medical Center, Cincinnati, OH, USA; Hong Li PhD, MPH, Group Director, Asia Pacific, Global Health Economics and Outcomes Research (GHEOR), Bristol-Myers Squibb Company, Wallingford, CT, USA, and Adjunct Associate Professors of University of Cincinnati Medical Center, USA and Duke-National University of Singapore (NUS) Graduate Medical School, Singapore
Course Description:
 Large administrative claims databases provide a unique opportunity to examine retrospectively the effects of drug use on clinical and economic outcomes in “real world” settings. This course will include discussions of the “ISPOR Checklist for Retrospective Database Studies” and selected topics related to sampling, bias, and analysis. The advantages and disadvantages of using these datasets to perform economic analyses and epidemiologic studies will be outlined. This introductory course is designed for those with little experience with database analysis.
Jeff J. Guo B. Pharm, PhD   Hong Li PhD, MPH
J. Guo
  H. Li
  Introduction to Quality of Life Assessment/Patient-Reported Outcomes
Faculty: Bruce Crawford MA, MPH, General Manager, Asia, Mapi Values, Meguro, Tokyo, Japan; Nutjaree Pratheepawanit Johns PhD, PharmD, Associate Professor, Pharmacy Practice Division, Director of Melatonin Research Group, Khon Kaen University, Khon Kaen, Thailand
Course Description: Definitions and concepts, methodologies, and practical methods for measuring patient-reported outcomes will be presented. The value of patient-reported outcomes assessment will be discussed. A strategy to aid in selecting appropriate instruments and the translation processes will be presented. Instrument development and validation will be discussed using practical examples and exercises, including “ISPOR Principles of Good Practice for the Translation and Cultural Adaptation Process for Patient-Reported Outcomes (PRO) Measures”. This introductory course is designed for individuals with little experience in quality of life/PRO studies.
B. Crawford   N. P. Johns
  Pharmaceutical/Biotech Pricing & Reimbursement Methodologies
Faculty: Jack Mycka, Global President and CEO, MME LLC, Montclair, New Jersey, USA; Manny Papadimitropoulos PhD, Director, Health Outcomes Research, Intercontinental Region and Japan, Eli Lilly Canada Inc., and Assistant Professor, Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada; Wen Chen PhD, Professor and Associate Dean, School of Public Health, Fudan University, Shanghai, China
Course Description: This course gives participants with a basic understanding of the key terminology and issues involved in pricing decisions and the principles of reimbursement methodologies. It covers the tools to document product value, the role of pharmacoeconomics and the differences in payment systems that help pricing decisions. Recent pharmaceutical spending patterns, trends and cost-containment measures will also be discussed taking account of the wider policy context. This introductory course is designed for those with limited experience in pharmaceutical pricing and reimbursement.
J. Mycka   W. Chen
M. Papadimitropoulos
1:00pm - 5:00pm AFTERNOON COURSES


Meta-Analysis and Systematic Literature Review
Faculty: Nathorn Chaiyakunapruk PharmD, PhD, Director of Center of Pharmaceutical Outcomes Research, and Associate Professor of Pharmacy, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand; Seokyung Hahn PhD, Assistant Professor of Medical Statistics, Medical Research Collaborating Center, Seoul National University, Seoul, South Korea
Course Description: Meta-analysis may be defined as the statistical analysis of data from multiple studies for the purpose of synthesizing and summarizing results, as well as for quantitatively evaluating sources of heterogeneity and bias. A systematic literature review often includes meta-analysis and involves an explicit, detailed description of how a review was conducted. This course highlights and expounds upon four key areas: 1) impetus for meta-analysis and systematic reviews, 2) basic steps to perform a quantitative systematic review, 3) statistical methods of combining data, and 4) appraisal and use of meta-analytic reports. This introductory/ intermediate course is designed for those with little experience with meta-analysis.

N. Chaiyakunapruk   S. Hahn
  Applied Modeling
Faculty: Mark Roberts MD, MPP, Professor and Chair, Health Policy & Management, University of Pittsburgh, Pittsburgh, PA, USA; Hsing Luh PhD, Professor, Department of Mathematical Sciences, National Chengchi University, Taipei, Taiwan
Course Description:This course is a hands-on introduction to the use of software in the creation and analysis of cost-effectiveness decision models. The basic techniques for decision tree modeling, simple Markov modeling and Monte Carlo simulation will be introduced. Useful techniques to manage variables and tables in TreeAge Pro, and to develop Excel dash­board will be demonstrated. This course is suitable for those who are familiar with the various modeling methods or who have taken the morning course “Introduction to Modeling”. All participants must bring a Windows laptop computer. A copy of TreeAge Pro Suite will be provided at the beginning of the course.
M. Roberts   H. Luh
  New! Utility Measures (Preference-Based Techniques)
Faculty: Andrew Lloyd DPhil, Director, Outcomes Research, Oxford Outcomes Ltd., Oxford, UK; Phantipa Sakthong PhD, Assistant Professor, Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand; Li Yang PhD, Associate Professor, Department of Health Policy and Management, School of Public Health, Peking University, Beijing, China
Course Description: During this course methods for measuring preference-based outcomes will be demonstrated, and important issues (such as potential insensitivity of generic instruments for disease-specific problems and to what extent adaptation of generic or disease-specific quality of life instruments may offer a solution) will be discussed. Finally, interpretation in the context of resource allocation will be discussed. This intermediate course is for those with some experience with quality of life mea­sures in health economic evaluation.
A. Lloyd   P. Sakthong
    L. Yang
  Budget Impact and Cost Analysis
Faculty: Scott D. Ramsey MD, PhD, Professor, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA, USA; Jeonghoon Ahn PhD, Director, Economic Evaluations, National Evidence-based healthcare Collaborating Agency, Seoul, South Korea
Course Description: This course will describe methods to determine the cost-of-illness of a health condition. Participants will learn how to estimate the impact of new health care technologies on disease-specific costs from different decision-maker perspectives. A discussion on “Principles of Good Practice for Budget Impact Analysis: Report of the ISPOR Task Force” will be included in this course. Case studies will be conducted to help better understand appropriate strategies. This intermediate course is designed for those with some experience with pharmacoeconomic analysis.
S. Ramsey   J. Ahn
  New! Adapting Cost-Effectiveness Data from Other Countries
Faculty: Michael Drummond PhD, Professor of Health Economics, Centre for Health Economics, University of York, Heslington, York, UK; Yot Teerawattananon MD, PhD, Leader, Health Intervention and Technology Assessment Program (HITAP), Ministry of Public Health, Nonthaburi, Thailand
Course Description: This course will discuss factors that make economic data more difficult than clinical data to adapt from other countries and the evidence on the variability of cost-effectiveness results across countries. Potential methods to provide solutions will be reviewed and their pros and cons will be discussed, including the report of the ISPOR Task Force “Trans­ferability of Economic Evaluations across Jurisdictions”. Finally, emerging international guidance for dealing with issues of transferability will be discussed. This intermediate course is designed for those with basic understanding of cost calculation and modeling.
M. Drummond   Y. Teerawattananon

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