ISPOR 16th ANNUAL EUROPEAN CONGRESS AWARDS WINNERS

 

The ISPOR Research Presentation Podium and Poster Awards were established in 1998 to recognize the scientific merit of podium and poster presentations of the ISPOR Annual International Meetings, Annual European Congresses, Asia-Pacific and Latin America Conferences.

This year, the ISPOR judges evaluated podium presentations and nominated poster presentations. All podium presentations are considered for an award. Poster presentations in the top 20%, based on abstract review score, are considered and eligible for a poster presentation award.
Evaluations of scientific merit were based upon the following criteria:

  • Background provides appropriate perspective / context for the subject
  • Objectives / research questions are clearly stated
  • Research design / methods / modeling is appropriate and transparent (scores on this will determine winners in case of ties)
  • Data sources and/or sampling procedures are clear and appropriate
  • Data analyses are appropriate
  • Research objectives are met/addressed
  • Implications of findings are discussed
  • Factual information is kept separate from interpretations or implications
  • Abstract is presented in an unbiased manner
  • Clarity of presentation

THE RECIPIENTS  ARE: . . .

ISPOR Best Podium Research Presentation Awards

Best General Podium Presentations

CV2 - APPLICATION OF BEHAVIOURAL ECONOMICS TO THE UNDERSTANDING OF ADHERENCE: DOES AN INDIVIDUAL'S TIME PREFERENCE INFLUENCE ADHERENCE TO MEDICATIONS?
Fargher EA, Morrison V, Plumpton CO, Hughes DA
Bangor University, Bangor, UK

A survey of 2272 hypertensive patients from 8 European countries found that time preference was a significant predictor of adherence to medications; consideration of individual time preference may have value in assessing patients’ likelihood of persisting with medicines and in the development of adherence enhancing interventions.

 

MD3 - DECISON MAKING UNDER UNCERTAINTY: COVERAGE WITH EVIDENCE DEVELOPMENT IN THE CONTEXT OF MEDICAL DEVICES
Sorenson C1, Drummond M2
1London School of Economics and European Health Technology Institute for Socio-Economic Research, London, UK, 2University of York, Heslington, UK

The presentation discussed the first study to examine and compare coverage with evidence development (CED) policies in different countries, with a focus on their application to medical devices. Given growing interest in CED internationally, the presentation highlighted some of the key challenges and opportunities faced by CED in general and for medical devices in particular as well as identified potential strategies for improvement.

CA1 - RESPONSIVENESS OF THE EQ-5D IN ONCOLOGY: A META-ANALYSIS
Smith AB1, Cocks K1, Taylor M2, Parry D3
1University of York, York, UK, 2York Health Economics Consortium, York, UK, 3AstraZeneca UK, Macclesfield, UK

The presentation provided an analysis of the responsiveness of EQ-5D in oncology, demonstrating that the instrument is not sensitive to change in health status and therefore caution should be exercised when using the EQ-5D for cost-effectiveness / benefit analyses in oncology clinical trials.


Best Student Podium Research Presentations

MO3 - MULTI-STATE STATISTICAL MODELLING TO QUANTIFY AN INDIVIDUAL-BASED MICRO SIMULATION MODEL FOR RADIOTHERAPY TREATMENT IN LUNG CANCER PATIENTS
Bongers ML*1, De Ruysscher D2, Oberije C3, Lambin P3, Uyl-de Groot CA4, Coupe VMH1
1VU University Medical Center, Amsterdam, The Netherlands, 2University Hospitals Leuven/KU Leuven, Leuven, Belgium, 3MAASTRO Clinic, Maastricht, The Netherlands, 4Erasmus University Rotterdam, Rotterdam, The Netherlands

For the evaluation of personalized medicine, multi-state statistical modelling is a usefull technique to obtain individualized transition rates and their joint uncertainty that are required to inform a micro-simulation model including patient heterogeneity.

CL3- VALIDATION OF SURROGATE ENDPOINTS IN ADVANCED SOLID TUMOURS: SYSTEMATIC REVIEW OF STATISTICAL METHODS, RESULTS, AND IMPLICATIONS FOR POLICY MAKERS
Ciani O1, Davis S2, Tappenden P2, Garside R3, Stein K1, Cantrell A2, Saad E4, Buyse M5, Taylor R1
1University of Exeter, Exeter, UK, 2University of Sheffield, Sheffield, UK, 3University of Exeter, Truro, UK, 4Dendrix, Sao Paulo, Brazil, 5IDDI, Louvain-la-Neuve, Belgium

This study emphasises the importance of building consensus on appropriate statistical techniques to examine surrogacy and on development of evaluation frameworks across all areas of medicine, across jurisdictions and scientific communities.

 

QL1 - MAPPING THE CCQ ONTO EQ-5D SCORES (IM)POSSIBLE?
Boland MRS1, van Boven JF2, Rutten-van Mölken MPMH1
1Erasmus University Rotterdam, Rotterdam, The Netherlands, 2University of Groningen, Groningen, The Netherlands

This study aims to develop a model to predict mean EQ-5D utilities from Clinical COPD Questionnaire (CCQ) scores in case of lacking utility data.

Best New Investigator Podium Research Presentations

CP2 - THE MULTIMODEL ENSEMBLE APPROACH TO REDUCING STRUCTURAL UNCERTAINTY IN DECISION ANALYTICAL MODELLING
Parham PE1, Hughes DA2
1Bangor University, Gwynedd, UK, 2Bangor University, Bangor, UK

Structural uncertainty in decision analytical modelling is a key challenge that has hitherto attracted insufficient attention, yet, to date, health economists have not fully embraced the potential of the multi-model paradigm to reduce (and quantify) structural uncertainty. In this presentation, we discuss this approach for decision analytical modelling and the key issues, as well as illustrating some of these ideas using a simple 2-state Markov model

PP4 - THE IMPORTANCE OF PATIENT-REPORTED OUTCOMES IN REIMBURSEMENT OF ORPHAN PRODUCTS IN EUROPE
Lyons EJ1, McGeagh J1, Es-Skali IJ2, Parmenter L1, Nijhuis T3, Boucher G1
1Quintiles Outcome, Reading, UK, 2Quintiles Consulting, Hoofddorp, The Netherlands, 3Quintiles, Hoofddorp, The Netherlands

CL1 - A COMPARISON OF METHODOLOGIES FOR ESTIMATING SURVIVAL IN PATIENTS TREATED WITH SECOND-GENERATION TYROSINE-KINASE INHIBITORS (TKIS) FOR CHRONIC MYELOID LEUKAEMIA (CML)
Pennington B1, Batty AJ1, Clifton-Brown E2
1BresMed, Sheffield, UK, 2Pfizer Ltd, Tadworth, UK

Our presentation compared overall survival estimation methods used in chronic myeloid leukaemia appraisals to highlight important challenges around handling structural uncertainty in health technology appraisal decisions.


ISPOR Best Poster Research Presentation Awards

Best General Poster Research Presentations

PIH18-COST-EFFECTIVENESS OF MATERNAL TOXOPLASMA SCREENING IN AUSTRIA: A DECISION-ANALYTIC MODEL
Prusa AR1;Walter E2;Pollak A1;Hayde M1, Kasper DC1
1Medical University of Vienna, Vienna, Austria, 2Institute for Pharmaeconomic Research, Vienna, Austria

PIH30-MEDICATION ADHERENCE AND ADVERSE HEALTH OUTCOMES IN COMMUNITY DWELLING OLDER PATIENTS
Cahir C1;Fahey T2;Teljeur C3, Bennett K4
1Trinity College Dublin, Dublin 8, Ireland, 2Royal College of Surgeons in Ireland, Dublin, Ireland, 3Health Information and Quality Authority, Dublin, Ireland, 4Trinity Centre for Health Sciences, Dublin, Ireland

This research determined the association between medication adherence and patient reported adverse outcomes including adverse drug events (ADEs), health related quality of life (HRQOL) and hospitalisation in an older community dwelling cohort in Ireland in 2010.

Developing methods to assist older adults in accurate and safe management of their medications may help to increase their quality of life and prevent costly hospital admissions.

PCN131-COST-EFFECTIVENESS OF BENDAMUSTINE-RITUXIMAB IN FIRST-LINE INDOLENT NHL: A PATIENT-LEVEL SIMULATION
Dewilde S1;Woods B2;Castaigne JG3;Parker C2, Dunlop W3
1SHE, Brussels, Belgium, 2Oxford Outcomes, Oxford, United Kingdom, 3Mundipharma International Limited, Cambridge, United Kingdom

This cost-utility-analysis, based on a patient level simulation mirroring treatment pathways for indolent-NHL patients demonstrated that bendamustine in combination with rituximab meets UK cost-effective thresholds for first line treatment compared to CHOP-R and CVP-R.


Best Student Poster Research Presentations

PIH41-POTENTIALLY INAPPROPRIATE PRESCRIBING (PIP) AND ITS ASSOCIATION WITH INSTRUMENTAL ACTIVITIES OF DAILY LIVING (IADL) IMPAIRMENT IN OLDER PEOPLE
Moriarty F1;Cahir C2;Fahey T1, Bennett K3
1Royal College of Surgeons in Ireland, Dublin, Ireland, 2Trinity College Dublin, Dublin 8, Ireland, 3Trinity Centre for Health Sciences, Dublin, Ireland

This research found that potentially inappropriate prescribing in older people was associated with increase odds of having a functional impairment (i.e. needing assistance with an activity such as doing household chores) and suggests the importance of addressing sub-optimal prescribing to improve patient outcomes.

PIN127-ASSESSING THE FISCAL CONSEQUENCES OF IMMUNIZING THE FEMALE AND MALE POPULATION AGAINST HUMAN PAPILLOMAVIRUS (HPV) IN GERMANY
Kotsopoulos N1
;Connolly M1, Remy V2
1Unit of PharmacoEpidemiology & PharmacoEconomics, Groningen, Netherlands, 2Sanofi Pasteur MSD, Lyon, France

PCV131-A RETROSPECTIVE STUDY COMPARING COMPLIANCE, PERSISTENCE, AND BLOOD PRESSURE CONTROL BETWEEN FREE-DRUG AND SINGLE-PILL COMBINATION THERAPIES IN KOREAN HYPERTENSIVE PATIENTS
Hong JM1;Kim EG1;Min K2;Min J3;Shin K4, Yang BM1
1Seoul National University, Seoul, South Korea, 2Ajou University School of Medicine, Suwon, South Korea, 3Institute of Health and Environment, Seoul National University, Seoul, South Korea, 4Novartis Korea, Seoul, Seoul, South Korea

Unlike the existing positive evidences, it was hard to find a significant increase in persistence or BP improvement with SPC therapy compared to FC in Korean hypertensive patients.

Best New Investigator Poster Research Presentations

PIN36 - HOW MUCH DENGUE COSTS TO BRAZIL? A RETROSPECTIVE ADMINISTRATIVE CLAIMS ANALYSIS FROM THE PUBLIC PAYER PERSPECTIVE
Silva MA; Fernandes RA; Takemoto M; Haas LC; Amaral LM; Vasconcellos JF, Menezes LP
ANOVA, Rio de Janeiro, Brazil

Despite Brazilian government efforts to control Dengue, it remains a major issue for the public health system, by the significant disease costs, hospitalization and mortality rates presented in this study.

PIN119-PARENTAL PREFERENCES FOR ROTAVIRUS VACCINATION AND POTENTIAL VACCINATION COVERAGE IN YOUNG CHILDREN: A DISCRETE CHOICE EXPERIMENT
Veldwijk J1;Lambooij MS2;Bruijning-Verhagen PCJ3;Smit HA3, de Wit GA4
1National institute for public health and the environment, Bilthoven, Netherlands, 2National Institute of Public Health and the Environment, Bilthoven, Netherlands, 3University Medical Center Utrecht, Utrecht, Netherlands, 4National Institute for Public Health and the Environment, Bilthoven, Netherlands

In this presentation, parental preferences for rotavirus vaccination and potential vaccination coverage in young children: a discrete choice experiment.

PCV92-THE COST-UTILITY OF CATHETER-BASED RENAL DENERVATION AS COMPARED TO CURRENT STANDARD OF CARE FOR RESISTANT HYPERTENSION IN BELGIUM
Jugrin AV1;Caekelbergh K1;Vanacker J2;Vancauwenberghe L2, Lamotte M1
1IMS Health HEOR, Vilvoorde, Belgium, 2MEDTRONIC INC., Brussels, Belgium

The analyses conducted support the cost-effectiveness of catheter-based renal denervation in Belgium, as an effective, minimally invasive procedure, alternative to current standard of care for refractory hypertension.

ISPOR would like to thank all the judges who have volunteered their time and efforts during the meeting to score podium and poster research presentations.

 

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