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Sunday 9 November 8.00-12.00 (4 hours)
Cost Estimation and Assessing Financial (Budget) Impact of New HealthCare
Technologies
Girona Room (-2 Level)
Faculty:
Josephine Mauskopf PhD, Division Director, Global Health
Economics, RTI Health Solutions, RTI International, RTP, NC, USA.; C.
Daniel Mullins PhD, Professor, University of Maryland, School of
Pharmacy, Baltimore, MD, USA
Course Description: This course will
describe techniques in pharmacoeconomics that focus on cost. This will
include methods to determine the cost-of-illness of a health condition
using a “top-down” or “bottom-up” approach. Participants will also learn
how to estimate the impact of new health care technologies on
disease-specific costs from different decision-maker perspectives.
Actuarial methods using straight-line projections and nonlinear trends
will be described. Both static and dynamic methods for estimating the
budget impact of adding a new drug to a health plan formulary will also be
presented. This course is designed for those with some experience with
pharmacoeconomic analysis.

Evidence-Based Health Care Reimbursement Systems
in Europe - NICE and Beyond
Mallorca Room (-1 Level)
Faculty: Christian Gericke,
MD, MSc, DTMH
Dept of Health Care Management, Technische Universität Berlin, Berlin,
Germany
Course description: In this course,
reimbursement systems for pharmaceutical products in Europe will be
discussed. For all health care systems, the amount of resources to devote
to health care is limited. An overview of main health care funding and
resource allocation mechanisms for different types of services -
hospitals, office-based physicians, and drugs - is given. Recent
pharmaceutical spending patterns and trends in major European Union
countries will be discussed taking account of the wider policy context. A
range of cost-containment measures for pharmaceuticals will be presented,
with a focus on pharmaceutical pricing strategies. The varying importance
of pharmacoeconomics in pharmaceutical reimbursement within the EU will be
discussed. Participants will have the possibility to apply the taught
course contents in country case studies. This course is designed for
those with little experience with European health care systems and
pharmaceutical pricing and reimbursement.

Value/Valuation in Measuring Outcomes
(Preference-Based Techniques)
Tibidabo Room (Mezzanine Level)
Faculty: Jan Busschbach PhD,
Department of Medical Psychology, Erasmus MC, Rotterdam, Psychotherapeutic
Centre ‘De Viersprong’, Rotterdam, The Netherlands
Course Description: This course offers
a unique combination of theory and practice that examines the explicit
valuations systems of generic instruments (including HUI, EQ-5D and SF-6D)
as well as those implicit in widely used condition-specific instruments
(including FACT-L, QLQC-30 and HADS). Examples from the published
literature will be discussed using a critical review framework designed to
test the status of such value systems. Practical experience of the
principal preference-based techniques used in valuing health outcomes,
such as willingness-to-pay, standard gamble, and time trade-off will be
offered as an integral part of the course. The course is designed for
those with at least an intermediate level experience of quality of life
issues and practice.

Advanced Pharmacoeconomic Modeling
Menorca Room (-1 Level)
Faculty: Uwe Siebert MPh, MSc, Harvard School of Public Health, Harvard
Center for Risk Analysis, Boston, MA, USA; Gaby Sroczynski, MPH, Decision
Scientist, Harvard Center for Risk Analysis, Harvard School of Public
Health, Boston, USA
Course Description: This course will present an in-depth discussion of
advanced pharmacoeconomic modeling techniques such as Monte Carlo
analysis, Markov modeling, and probabilistic sensitivity analysis. This
course
is designed for those with experience with modeling techniques.

Meta-Analysis and Systematic Literature Review - Introduction
Roses Room (-2 Level)
Faculty: Maite Artes MSc, General Manager, ADELPHI TARGIS, Barcelona,
Spain; Mateu Serra-Prat MD, MPH, Head of the Research Unit, Consorci
Sanitari del Maresme CSdM, Barcelona, Spain
Course Description: Meta-analysis may be defined as the statistical
analysis of data from multiple studies for the purpose of synthesizing and
summarizing results, as well as for quantitatively evaluating sources of
heterogeneity and bias. A systematic literature review often includes
meta-analysis and involves an explicit, detailed description of how a
review was conducted. This short course highlights and expounds upon four
key areas: 1) impetus for meta-analysis and systematic reviews; 2) basic
steps to perform a quantitative systematic review; 3) statistical methods
of combining data; and 4) appraisal and use of meta-analytic reports. The
material is motivated via applications in pharmacoeconomics, outcomes
research, and clinical studies from the published literature and
hypothetical examples. Interactive exercises are part of the course. This
course is designed for those with little experience

The Analysis and Interpretation of
Quality of Life and Patient Reported Outcomes
Faculty:
Linda Abetz MA,
Research Director, Mapi Values, Bollington, UK;
Bruce Crawford MA, MPH, Project Director, Mapi Values, Boston, MA,
USA
Course Description:
This course is
designed to provide a range of methods that may help to solve common
problems encountered with Patient Reported Outcomes. These include
an overview of psychometric validation methods (including a brief
overview of Rasch analysis), missing data analysis techniques, and a
variety of methods to assess
minimally clinically important differences. Specific examples will be
used throughout the course and participants will be asked to complete a
short exercise. This course is designed for
individuals with little experience with quality-of-life studies.
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