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Program - Monday 22 October 2007
 

All conference attendants please use Angelsea Road!

8:00-9:00
Contributed Poster Presentations – Session II Viewing
  See Poster Presentations in Session II
   
9:00–10:30
Second Plenary Session

PATIENT REPORTED OUTCOMES: A EUROPEAN PERSPECTIVE

Moderator: Diane Wild MSc, Director, Oxford Outcomes, Oxford, UK
Speakers: Mira Pavlovic MD, Coordinator of Scientific Advice, DEMEB, Agence Française de Sécurité Sanitaire des Produits de Santé (Afssaps), Saint-Denis Cedex, France
John Brazier PhD, Professor of Health Economics, The University of Sheffield, SCHARR, Sheffield, UK
Clare McGrath, Senior Director, Outcomes Strategy - Europe, Canada, Africa and Middle East, Pfizer Tadworth, Surrey, UK
The use of patient reported outcomes has received considerable discussion recently, following the guidance issued by the Food and Drug Administration. The objective of this session is to discuss the role of PROs in Europe, given the slightly different views taken by the European Medicines Evaluation Agency (EMEA) and the fact that several national reimbursement agencies also consider quality of life data in reaching their decisions. Is their perspective different from that of the licensing agencies
10:30-10:45
Break, Exhibits & Contributed Poster Presentations - Session II Viewing
  See Poster Presentations in Session II
 
10:45-11:45
Contributed Podium Presentations - Session I (4 podium groups with 4 presentations per group)

 

Cardiovascular Disease I

CV1

POST-AMI DRUG THERAPY PERSISTENCE AND RISK OF REINFARCTION IN A MEDICAID POPULATION

 

Shaya FT, Gu A

 

University of Maryland School of Pharmacy, Baltimore, MD, USA

   

CV2

COST-EFFECTIVENESS OF ROSUVASTATIN VERSUS ATORVASTATIN, SIMVASTATIN, AND PRAVASTATIN FROM A CANADIAN HEALTH CARE PERSPECTIVE

 

Costa-Scharplatz M1, Beamer B2, Frial T2, Gandhi SK3

 

1AstraZeneca, Södertälje, Sweden, 2AstraZeneca, Mississauga, ON, Canada, 3AstraZeneca, LP, Wilmington, DE, USA

   

CV3

DO DIFFERENCES IN DOSE IMPACT ADHERENCE TO SINGLE-PILL AMLODIPINE/ATORVASTATIN VERSUS 2-PILL AMLODIPINE AND ATORVASTATIN?

 

Tang SSK1, Patel BV2, Leslie RS2, Thiebaud P2, Nichol MB3, Solomon HA1, Trainer JB1, Foody JM4

 

1Pfizer Inc, New York, NY, USA, 2MedImpact Healthcare Systems, Inc, San Diego, CA, USA, 3University of Southern California, Los Angeles, CA, USA, 4Yale University, New Haven, CT, USA

   

CV4

BENEFIT/RISK OF IRBESARTAN/HYDROCHLOROTHIAZIDE AS FIRST-LINE TREATMENT OF SEVERE HYPERTENSION

 

Lapuerta P1, Gomez A2, Franklin S3

 

1Bristol-Myers Squibb, Princeton, NJ, USA, 2Bristol-Myers Squibb, Hopewell, NJ, USA, 3University of California at Irvine, Los Angeles, CA, USA

 

 

Economics of Diabetes

   

ED1

COST-EFFECTIVENESS OF INSULIN DETEMIR VERSUS NPH FOR TYPE 1 DIABETES PATIENTS IN A GERMAN SETTING. A MODELING EVALUATION BASED UPON RESULTS FROM A META-ANALYSIS.

 

Kotchie R1, Scheijbeler H1, Aagren M2, Nielsen S2, Valentine WJ3, Goodall G3

 

1IMS Health, London, UK, 2Novo Nordisk A/S, Virum, Denmark, 3IMS Health, Basel, Switzerland

 

 

ED2

LONG-TERM COST-UTILITY ANALYSIS OF INSULIN ASPART (NOVORAPID®) VERSUS HUMAN SOLUBLE INSULIN IN TYPE 2 DIABETES PATIENTS IN THE GERMAN SETTING

 

Goodall G1, Valentine WJ1, Townsend C2, Kotchie R3, Nielsen S2, Erny-Albrecht K1

 

1IMS Health, Basel, Switzerland, 2Novo Nordisk A/S, Virum, Denmark, 3IMS Health, London, UK

   

ED3

DIFFERENCES IN HEALTH RELATED RESOURCE USE IN THE 6 MONTHS PRIOR TO AND AFTER INSULIN INITIATION IN PATIENTS WITH TYPE 2 DIABETES IN GERMANY AND UK: DATA FROM THE INSTIGATE STUDY

 

Timlin L1, Tynan A1,Simpson A1, Jones S2, Liebl A3

 

1Eli Lilly and Company Limited, Surrey, UK, 2The James Cook University Hospital, Middlesborough, UK, 3Fachklinik Bad Heilbrunn, Bad Heilbrunn, Germany

   

ED4

THE RELATIVE COST EFFECTIVENESS OF SWITCHING TO INSULIN GLARGINE VERSUS NPH INSULIN IN INSULIN NAIVE AND NON INSULIN NAIVE TYPE 2 DIABETES PATIENTS USING UK REAL LIFE DATA

 

McEwan P1, Mehin N2, Tetlow AP3, Sharplin P3

 

1Cardiff University, Cardiff, South Glamorgan, UK, 2sanofi-aventis, Paris, France, 3Cardiff Research Consortium, Cardiff, South Glamorgan, UK

 

 

Methods & Concepts

   

MC1

ASSESSING THE GENERALISABILITY OF COST EVALUATION RESULTS USING THE EUCLIDEAN METRIC AND PRINCIPAL COMPONENTS ANALYSIS: LESSON FROM A HIGH-COST INNOVATION IN ONCOLOGY

 

Perrier L1, Pommier P1, Carrère MO2, Sylvestre Baron P3

 

1Léon Bérard Cancer Centre, Lyon, France, 2University of Lyon, Lyon, France, 3University of Lyon, Ecully, France

   

MC2

BAYESIAN MODELING OF RESOURCE USE ALONGSIDE MULTINATIONAL RANDOMISED CLINICAL TRIALS

 

Gauthier A1, Manca A2, Anton SF3, Dewberry H4

 

1i3 Innovus, Uxbridge, Middlesex, UK, 2University of York, York, UK, 3Boehringer-Ingelheim, Ridgefield, CT, USA, 4Boehringer Ingelheim Limited, Bracknell, Berkshire, UK

   

MC3

THE DEVELOPMENT OF AN INCREMENTAL WILLINGNESS TO PAY CURVE DERIVED FROM A DISCRETE CHOICE EXPERIMENT

 

Regier DA1, Marra CA2, Ryan M1

 

1University of Aberdeen, Aberdeen, Scotland, UK, 2University of British Columbia, Vancouver, BC, Canada

   

MC4

COMPARISON OF THREE INSTRUMENTS ASSESSING THE QUALITY OF ECONOMIC EVALUATIONS

 

Gerkens S, Crott R, Beguin C, Closon MC, Horsmans Y

 

Université Catholique de Louvain, Brussels, Belgium

 

 

Patient Reported Outcomes I

   

PR1

RECOMPUTING VALUES FOR EQ-5D IN ACCORDANCE WITH NICE APPRAISAL GUIDANCE

 

Kind P

 

University of York, York, UK

   

PR2

NON-PERSISTENT USE OF ORAL ANTIDIABETIC DRUGS LEADS TO 20% DECREASED CHANCE OF HBA1C GOAL-ATTAINMENT IN DAILY CLINICAL PRACTICE

 

Koerselman J1, van der Bij S1, Erkens JA1, Kessabi S2, Groot MT3, Penning-van Beest FJ1, Herings RM1

 

1PHARMO Institute, Utrecht, Utrecht, The Netherlands, 2Novartis Pharma AG, Basel, Switzerland, 3Novartis Pharma B.V, Arnhem, The Netherlands

   

PR3

PATIENTS', PARENTS', AND PHYSICIANS' RISK-BENEFIT TRADE-OFF PREFERENCES FOR CROHN'S DISEASE TREATMENTS

 

Johnson FR1, Ozdemir S1, Mansfield C1, Hauber AB1, Hass SL2, Siegel CA3, Sands BE4, Miller DW2

 

1RTI International, RTP, NC, USA, 2Elan Pharmaceuticals Inc, San Diego, CA, USA, 3Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA, 4Massachusetts General Hospital, Boston, MA, USA

   

PR4

BACK PAIN IN GERMANY: ARE THERE DIFFERENCES CONCERNING HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN PATIENTS TREATED ACCORDING TO GUIDELINES, GUIDELINE INDEPENDENT AND PATIENT SELF-TREATMENT?

 

Breitscheidel L1, Stridde E2, Kreyenberg K1, Benter U1, Eichmann F1

 

1Kendle GmbH, Munich, Germany, 2Pfizer Pharma GmbH, Karlsruhe, Germany

 

 

  See all podiums

 

 

11:45-12:00
Break, Exhibits & Contributed Poster Presentations – Session II Viewing
  See Poster Presentations in Session II
 
12:00-13:00
Contributed Podium Presentations – Session II (4 podium groups with 4 presentations per group)

 

Cancer

   

CN1

USING THE FACT-NEUROTOXICITY TO EVALUATE QUALITY OF LIFE IN CANCER PATIENTS FROM ACROSS THE GLOBE

 

Eremenco S, Du H, Arnold B, Herzberg T, Cella D

 

Evanston Northwestern Healthcare, Evanston, IL, USA

   

CN2

DEVELOPMENT AND VALIDATION OF OPTIMALLY WEIGHTED MEASURES OF GLOBAL HEALTH-RELATED QUALITY OF LIFE (QOL) AND UTILITY BASED ON A CANCER-SPECIFIC QOL INSTRUMENT

 

Grimison PS, Simes RJ, Stockler MR

 

NHMRC Clincial Trials Centre, University of Sydney, CAMPERDOWN, NSW, Australia

   

CN3

EFFECTIVENESS OF EPOETIN ALPHA VERSUS DARBEPOETIN IN CHEMOTHERAPY-INDUCED ANAEMIA IN THE GERMAN SETTING

 

Ezzat N1, Brüggenjürgen B2, Willich SN2

 

1Alpha Care GmbH, Celle, Germany, 2Charite University Medical Center, Berlin, Germany

   

CN4

COST-EFFECTIVENESS OF PEGYLATED LIPOSOMAL DOXORUBICIN VS. CONVENTIONAL DOXORUBICIN IN AVOIDANCE OF CARDIOTOXICITY FOR METASTATIC BREAST CANCER IN THE FIRST TREATMENT YEAR

 

Singer ME1, Sandor DW2, Reardon G3

 

1Case Western Reserve University School of Medicine, Cleveland, OH, USA, 2Touro University College of Medicine, Hackensack, NJ, USA, 3Informagenics, LLC, Worthington, OH, USA

 

 

Economic Studies I

ES1

INCREMENTAL DIFFERENCES IN RESOURCE UTILIZATION AND COSTS OF TREATING PERSONS INFECTED WITH HIV IN A LOW SOCIOECONOMIC NEIGHBORHOOD

 

Johnston KM1, Levy A1, Lai C2, Briggs A3, Kerr T2, Montaner JS2, Tyndall M1

 

1University of British Columbia, Vancouver, BC, Canada, 2British Columbia Centre for Excellence in HIV/AIDS Research, Vancouver, BC, Canada, 3University of Glasgow, Glasgow, UK

   

ES2/
PMH44

COSTS AND OUTCOMES OF ATYPICAL ANTIPSYCHOTICS FOR THE TREATMENT OF ACUTE SCHIZOPHRENIA

  Leeuwenkamp O1, Morlock R2, Bell CF3, Brogan A4, Mauskopf J4
  1NV Organon, Molenstraat, Oss, The Netherlands, 2Pfizer Inc, Ann Arbor, MI, USA, 3GlaxoSmithKline, Memphis, TN, USA, 4RTI Health Solutions, Research Triangle Park, NC, USA
   

ES3

COST-EFFECTIVENESS OF FIRST EYE CATARACT SURGERY IN ELDERLY WOMEN: A RANDOMISED CONTROLLED TRIAL

 

Sach TH1, Foss AJ2, Gregson RM2, Zaman A2, Osborn F2, Masud T2, Harwood RH2

 

1University of Nottingham, Nottingham, UK, 2Nottingham University Hospitals NHS Trust, Nottingham, UK

   

ES4/
PSU2

THE RELATIVE COST-EFFECTIVENESS OF THE FENTANYL HCL PATIENT-ACTIVATED TRANSDERMAL SYSTEM (ITS) IN ACUTE POST-OPERATIVE PAIN MANAGEMENT (POPM) IN GREECE

 

Yfantopoulos I1, Papanicolaou S2, Papagianopoulou V1, Van Bellinghen LA3, Annemans L4

 

1University of Athens, Athens, Greece, 2Janssen-Cilag Pharmaceutical SACI, Athens, Greece, 3IMS HEOR, Brussels, Belgium, 4Ghent University, Ghent, Belgium

 

 

Patient Reported Outcomes II

   

PR5

VALIDATION OF POMS QUESTIONNAIRE IN POSTMENOPAUSAL WOMEN

 

Yu H1, Wyrwich K2, Bobula J1

 

1Wyeth Research, Collegeville, PA, USA, 2Saint Louis University, St. Louis, MO, USA

   

PR6

PATIENT CHARACTERISTICS IMPACTING QUALITY OF LIFE (EQ-5D) OF FEMALES WITH STRESS URINARY INCONTINENCE SYMPTOMS

 

Tincello D1, Sculpher M2, Tunn R3, Quail D4, Timlin L4, Manning M5

 

1University of Leicester, Leicester, UK, 2University of York, York, UK, 3St Hedwig Hospitals, Berlin, Germany, 4Eli Lilly and Company Limited, Surrey, UK, 5Lilly Deutschland, BadHomburg, Germany

   

PR7

PATIENT'S PREFERENCES FOR OSTEOPOROSIS DRUG TREATMENT: A DISCRETE CHOICE EXPERIMENT

 

De Bekker-Grob EW, Essink-Bot ML, Meerding WJ, Pols HAP, Koes BW, Steyerberg EW

 

Erasmus MC, Rotterdam, The Netherlands

   

PR8

EVALUATION OF IMPROVEMENT IN HEALTH-RELATED QUALITY OF LIFE USING ORAL MESALAZINE ALONE OR IN COMBINATION WITH A MESALAZINE ENEMA IN ACTIVE ULCERATIVE COLITIS: RESULTS FROM A RANDOMISED CONTROLLED TRIAL

 

Nielsen SK1, Currie CJ2, Connolly MP1, Bhatt A1

 

1Ferring International Center, Saint-Prex, Switzerland, 2Cardiff University, Cardiff, UK

 

 

Surgery

SU1

COST-EFFECTIVENESS OF CYCLOOXYGENASE-2 INHIBITOR PARECOXIB COMPARED TO OPIOIDS AFTER NONCARDIAC SURGERY IN THE UK

 

Remák E1, Muszbek N2, Manson SC3, Zlateva G4, Chen C4

 

1United Biosource Corporation, Budapest, Hungary, 2UnitedBiosource Corporation, London, UK, 3United BioSource Corporation, London, UK, 4Pfizer Inc, New York, NY, USA

   

SU2

MICRO-COSTING OF SURGICAL PROCEDURES RELATED TO INTRACEREBRAL HAEMORRHAGE IN A UK HEALTH CARE SETTING

 

Manson SC1, De Cock E2, Jenkins AJ3, Twena N4

 

1United BioSource Corporation, London, UK, 2United BioSource Corporation, Barcelona, Spain, 3Newcastle General Hospital, Newcastle upon Tyne, UK, 4Novo Nordisk Ltd, Crawley, West Sussex, UK

   

SU3

NINE YEAR FOLLOW UP OF BIRMINGHAM HIP RESURFACING IN CONTEXT OF SURVIVAL AND COMPLICATIONS.

 

Aulakh TS, Robinson EV, Richardson JB

 

RJAH Orthopaedic Hospital, Oswestry, Shropshire, UK

   

SU4

THE COST-EFFECTIVENESS OF TITANIUM CAGE VERSUS FEMORAL RING ALLOGRAFT IN CIRCUMFERENTIAL LUMBAR FUSION: A RANDOMISED CONTROLLED TRIAL

 

Sach TH1, Steele NA2, Hegarty J2, Soegaard R3, Freeman BJ2

 

1University of Nottingham, Nottingham, UK, 2Nottingham University Hospitals NHS Trust, Nottingham, UK, 3University of Aarhus, Aarhus, Denmark

 

 

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13:00-14:30
Lunch, Exhibits & Contributed Poster Presentations – Session II Viewing
  See Poster Presentations in Session II
   
13:30-14:30
Educational Symposium sponsored by IMS Health
Can You Hear Me Now?


Techniques for effectively communicating value to internal and external decision makers.

Description
In an environment characterized by increasing competition on the one side and cost pressures from payers and governments on the other, pharmaceutical companies need to be become more effective in return on investment and alignment of their global capabilities in order to continue to win in the market place.  One key capability of increasing importance in this effort is HEOR.

For HEOR to be relevant/valuable and successful in this role, we have to learn to effectively communicate value.  And to do that, we must first have something effective to communicate.  To meet this challenge IMS has developed the concept of the two bookends of HEOR:  value planning at the beginning and value communication at the end of all value demonstration projects.  These allow us to enhance the value that the HEOR function adds at the corporate, therapeutic and brand level.  This workshop will discuss these two bookends.

13:30 - 13:40 
OPENING REMARKS


Moderators: Jonothan C. Tierce, CPhil, Practice Lead, Americas, IMS Health, Health Economics & Outcomes Research; Claude LePen, PhD, Professor of Economics, Paris-Dauphine University & Member of the Strategic Committee of IMS France

The speakers will briefly address the growing opportunity for HEOR to become a key leader within the pharmaceutical industry.

13:40 - 13:55
THE NEED TO BECOME MORE EFFECTIVE IN PLANNING AND COMMUNICATING VALUE


Speaker: Adrian Kielhorn, PharmD, International Economic Strategy Leader, F.Hoffmann-La Roche AG

The speaker will discuss the need to become more effective in terms of value planning and value communication and he will provide examples of how HEOR can increase their value within pharmaceutical companies by being more effective.

13:55 - 14:10
CONCEPTS FOR MAXIMIZING THE VALUE DELIVERED BY HEOR TEAMS


Speaker: Elizabeth Hazard, PhD, Principal, IMS Health, Health Economics & Outcomes Research

The speaker will discuss the Value Development Plan and Value Communications Programs.  She will present the two concepts, how they are developed, how they help to maximize the value delivered by HEOR groups as well as enhance the perceived value of products within the market place.

14:10 - 14:30
DISCUSSION / Q&A

 
14:30-15:30
Contributed Podium Presentations – Session III (4 podium groups with 4 presentations per group)

 

Diabetes

   

DB1

IMPACT OF ROSIGLITAZONE THERAPY ON THE LIPID PROFILE AND LIPID-LOWERING TREATMENT IN TYPE 2 DIABETES PATIENTS

 

Suh DC1, Huang J1, Nocea G2, Yin D3, Krishnarajah G3

 

1Rutgers University, Piscataway, NJ, USA, 2MSD Spain, Madrid, Spain, 3Merck & Co., Inc, Whitehouse Station, NJ, USA

   

DB2

COMPARING BRITISH AND GERMAN DIABETES GUIDANCE WITH RESPECT TO LONGTERM OUTCOMES AND ASSOCIATED COSTS: RESULTS FROM THE EAGLE DIABETES SIMULATION MODEL

 

Mueller E1, Huppertz E2, Stridde E3

 

1Analytica International, Loerrach, Germany, 2Consultant HE&RO, Niedererbach, Germany, 3Pfizer Pharma GmbH, Karlsruhe, Germany

   

DB3

CLINICAL AND PATIENT REPORTED OUTCOMES OVER THE FIRST 6 MONTHS OF INSULIN THERAPY IN PATIENTS WITH TYPE 2 DIABETES IN GERMANY AND UK: DATA FROM THE INSTIGATE STUDY

 

Timlin L1, Tynan A1, Simpson A1, Liebl A2, Jones S3

 

1Eli Lilly and Company Limited, Surrey, UK, 2Fachklinik Bad Heilbrunn, Bad Heilbrunn, Germany, 3The James Cook University Hospital, Middlesborough, UK

   

DB4

TREATMENT ADHERENCE AND BARRIERS TO ADHERENCE ARE ASSOCIATED WITH GLYCEMIC CONTROL AND EXPERIENCE OF HYPOGLYCEMIA AMONG PATIENTS WITH TYPE-2 DIABETES MELLITUS (T2DM) ON ORAL ANTI-HYPERGLYCEMIC AGENTS (OHA) IN EUROPE

 

Alvarez-Guisasola F1, Martin Castillo F2, Krishnarajah G3, Lyu R4, Mavros P4, Yin D4

 

1Centro de Salud La Calzada II, Gijón, Spain, 2Hospital General de Móstoles, Madrid, Spain, 3Merck & Co, Whitehouse Station, NJ, USA, 4Merck & Co., Inc, Whitehouse Station, NJ, USA

 

 

Economics of Cancer

EC1

RESOURCE USE AND COST OF DIAGNOSTIC WORKUP OF WOMEN WITH SUSPECTED BREAST CANCER

 

Lee DW1, Stang PE2, Goldberg GA3, Haberman M4

 

1GE Healthcare, Waukesha, WI, USA, 2Independent Consultant, Blue Bell, PA, USA, 3i3 Innovus, Santa Monica, CA, USA, 4Thomson Medstat, Washington, DC, USA

   

EC2

AN ECONOMIC EVALUATION OF DASATINIB AS A TREATMENT FOR CHRONIC PHASE CHRONIC MYELOID LEUKAEMIA IN SCOTLAND

 

Taylor MJ1, Minda K2, Cerri KH3, Davis C4, Kan HJ5, Ray S6

 

1University of York, York, UK, 2Bristol-Myers Squibb Pharmaceuticals, Uxbridge, UK, 3Bristol-Myers Squibb International Corporation, Braine l'Alleud, Braine l'Alleud, Belgium, 4Bristol-Myers Squibb, Wallingford, CT, USA, 5Bristol Myers Squibb, Wallingford, CT, USA, 6Bristol-Myers Squibb Pharmaceuticals, Wallingford, CT, USA

   

EC3

COST-MINIMIZATION ANALYSIS OF CAPECITABINE + OXALIPLATIN (XELOX) VS. INFUSIONAL 5-FU/LV + OXALIPLATIN (FOLFOX-6) AS FIRST-LINE TREATMENT FOR METASTATIC COLORECTAL CANCER (MCRC) IN THE FRENCH SETTING

 

Perrocheau G1, Ducreux M2, Hebbar M3, Ychou M4, Lledo G5, Conroy T6, Faroux R7, Douillard JY8, Pacull A9

 

1Centre René Gauducheau, Saint-Herblain, France, 2Institut Gustave Roussy, Villejuif, France, 3CHU, Lille, France, 4Centre Val d’Aurelle, Montpellier, France, 5Clinique Saint-Jean, Lyon, France, 6Centre Alexis Vautrin – Centre regional de Lutte contre le Cancer, Vandoeuvre les Nancy, France, 7Centre Hospitalier Départemental – Les Oudairies, La Roche sur Yon, France, 8Centre René Gauducheau, Nantes, France, 9Roche, Neuilly-sur-Seine, France

   

EC4

COST-EFFECTIVENESS AND COST-UTILITY OF RITUXIMAB MAINTENANCE THERAPY FOR PATIENTS WITH RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA IN FRENCH SETTING

 

Pacull A1, Coudray-Omnes C1, Brice P2, Deconinck E3, Le Pen C4, Miadi-Fargier H5

 

1Roche, Neuilly-Sur-Seine, France, 2Saint-Louis Hospital, Paris, France, 3INSERM U-645 Université de Franche-Comté CHU Jean Minjoz IFR 133, Besançon, France, 4Dauphine University, Paris, France, 5AREMIS - aegisnet, Neuilly sur Seine, France

 

 

Health Care Use & Policy Studies

HP1

HEALTH SYSTEM CORRELATES OF RECEIPT OF RADIATION AFTER BREAST CONSERVING SURGERY IN LOW-INCOME MEDICAID-ENROLLED WOMEN

 

Anderson RT1, Balkrishnan R2

 

1Wake Forest University School of Medicine, Winston Salem, NC, USA, 2The Ohio State University College of Pharmacy, Columbus, OH, USA

   

HP2

ASSOCIATIONS BETWEEN NEGATIVE SYMPTOMS, SERVICE USE, AND COSTS FOR PATIENTS WITH SCHIZOPHRENIA IN FIVE EUROPEAN COUNTRIES

 

Leeuwenkamp O1, Knapp M2, McCrone P3

 

1NV Organon, Molenstraat, Oss, The Netherlands, 2London School of Economics, London, UK, 3King's College London, London, UK

   

HP3

ASSESSING THE IMPACT OF A NATIONAL DRUG BENEFIT PROGRAM ON THE USE OF GENERIC DRUGS AND DIFFERENT THERAPEUTIC CLASSES

 

Zhang JX1, Yin W1, Sun SX2, Lee KY2, Meltzer DO1, Alexander GC1

 

1University of Chicago, Chicago, IL, USA, 2Walgreens Health Services, Deerfield, IL, USA

   

HP4

PROMOTING A DRUG'S HEALTH ECONOMIC ADVANTAGES IN MEDICAL JOURNAL ADVERTISING IN THE U.S.: A REVIEW OF 3,500 ADS FROM 1990-2006

 

Neumann PJ, Palmer JA, Timm AR

 

Tufts-New England Medical Center, Boston, MA, USA

 

 

Musculoskeletal Disease

MD1

IMPACT OF ANTI-TUMOR NECROSIS FACTORS ON HEALTHCARE RESOURCE UTILIZATION IN PATIENTS WITH IMMUNE-MEDIATED INFLAMMATORY DISEASES

 

Tang B1, Rahman MI1, Stephenson JJ2, Quimbo RA2, Thompson HC1, Naim A1, Dabbous O1

 

1Centocor, Inc, Horsham, PA, USA, 2HealthCore Inc, Wilmington, DE, USA

   

MD2

ECONOMIC CONSEQUENCES OF PROVIDING RITUXIMAB AS A TREATMENT ALTERNATIVE FOR RHEUMATOID ARTHRITIS IN THE NETHERLANDS

 

Pompen M1, Diamantopoulos A2, Kievit W3, Moers R4, Kielhorn A5

 

1Roche Netherland BV, Woerden, The Netherlands, 2IMS Health, London, UK, 3Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, 4Roche Nederland BV, Woerden, The Netherlands, 5F. Hoffmann-La Roche AG, Basel, Switzerland

   

MD3

CHANGES IN BODYWEIGHT AND ASSOCIATED DOSING REQUIREMENTS FOR RHEUMATOID ARTHRITIS PATIENTS RECEIVING INFLIXIMAB - RESULTS FROM ANALYSIS OF THE BRITISH SOCETY FOR RHEUMATOLOGY'S BIOLOGICS REGISTER (BSRBR)

 

Gibbons CJ, Morris J, Abhyankar B

 

Schering-Plough, Welwyn Garden City, UK

   

MD4

COST-EFFECTIVENESS OF BONE DENSITOMETRY SCREENING COMBINED WITH ALENDRONATE THERAPY FOR THOSE WHO HAVE OSTEOPOROSIS

 

Hiligsmann M, Bruyère O, Ethgen O, Reginster JY

 

University of Liège, Liège, Belgium

 

 

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15:30-15:45
Break, Exhibits & Contributed Poster Presentations – Session II Viewing
  See Poster Presentations in Session II
 
15:45-16:45
Contributed Podium Presentations – Session IV (4 podium groups with 4 presentations per group)
 

 

Cardiovascular Disease II

CV5

FONDAPARINUX (FOND) VERSUS ENOXAPARIN (ENOX) FOR PREVENTION AND TREATMENT OF VENOUS THROMBOEMBOLIC EVENTS (VTE) IN PATIENTS UNDERGOING MAJOR ORTHOPEDIC SURGERY OF THE LOWER LIMBS (MOSLL) IN GERMANY: ECONOMIC EVALUATION FROM THE HOSPITAL PERSPECTIVE

 

Schaedlich P1, Briswalter S2, Brecht J3

 

1Informed, Itzehoe, Germany, 2GlaxoSmithKline, Munich, Germany, 3Informed, Ingolstadt, Germany

   

CV6

SIROLIMUS-ELUTING VERSUS BARE-METAL CORONARY STENTS: 18-MONTH CLINICAL AND ECONOMIC OUTCOMES OF A CONTROLLED STUDY FOR THE REDUCTION OF CORONARY RESTENOSIS

 

McBride D, Brüggenjürgen B, Roll S, Willich SN

 

Charité University Medical Center, Berlin, Germany

   

CV7

COMPARISON OF THE COST-EFFECTIVENESS OF SEROLIMUS-ELUTING VERSUS BARE-METAL STENTS IN RELATION TO PATIENT CORONARY ARTERY DISEASE STATUS

 

Brüggenjürgen B, McBride D, Roll S, Reinhold T, Willich SN

 

Charité University Medical Center, Berlin, Germany

   

CV8

THE COST-EFFECTIVENESS (COST-UTILITY) OF EPROSARTAN IN HYPERTENSIVE PATIENTS WITH CEREBROVASCULAR DISEASE IN BELGIUM, GERMANY, SPAIN, UK, AND SWEDEN

 

Schwander B1, Lindgren P2, Gradl B3

 

1Analytica International, Loerrach, Germany, 2I3 innovus, Stockholm, Sweden, 3Solvay Pharmaceuticals GmbH, Hannover, Germany

 

 

Economic Studies II

ES5

DOES ARTHROSCOPIC ACROMIOPLASTY PROVIDE ANY ADDITIONAL VALUE IN THE TREATMENT OF SHOULDER IMPINGEMENT SYNDROME? A TWO-YEAR RANDOMIZED CONTROLLED TRIAL

 

Aronen PI

 

University of Helsinki, Helsinki, Finland

   

ES6

COST COMPARISON BETWEEN HAEMODIALYSIS AND PERITONEAL DIALYSIS IN NORWAY FOR PATIENTS WHO CAN USE EITHER TREATMENT MODALITY

 

Nyhus K, Kristensen FKO, Merméjean P, Sverre JM

 

PharmEcon, Asker, Akershus, Norway

   

ES7

ASSESSMENT OF LONG-RUN ECONOMIC BENEFITS ASSOCIATED WITH IN-VITRO FERTILIZATION (IVF) FUNDING DECISIONS: A SIMPLIFIED LIFETIME TAX CALCULATION

 

Connolly MP1, Hoorens S2, Gallo F2, Ledger W3

 

1Ferring International Center, Saint-Prex, Switzerland, 2RAND Europe, Cambridge, UK, 3University of Sheffield, Sheffield, UK

   

ES8

COST-EFFECTIVENESS OF DARUNAVIR/R IN HIGHLY TREATMENT-EXPERIENCED HIV/AIDS PATIENTS IN DIFFERENT EUROPEAN HEALTH CARE SETTINGS

 

Moeremans K1, Annemans L2, Smets E3, Wyffels V4, Lothgren M5, Allegri G6

 

1IMS HEOR, Brussels, Belgium, 2Ghent University, Gent, Belgium, 3Johnson & Johnson Pharmaceutical Services, Inc, Beerse, Belgium, 4Janssen Cilag NV, Berchem, Belgium, 5JANSSEN-CILAG, Sollentuna, Sweden, 6TIBOTEC a division of JANSSEN-CILAG SpA Italy, Cologno Monzese, Italy

 

 

Economics of Neurological Disease

ND1

COST-EFFECTIVENESS OF INTRATHECAL BACLOFEN THERAPY VERSUS CURRENT THERAPIES IN DISABLED SPASTICITY

 

Beresniak A1, Bensmail D2, Ward A3, Wissel J4, Motta F5, Saltuari L6, Lissens J7, Cros S7

 

1Data Mining International, Geneva, Switzerland, 2Raymond Poincare Hospital, Garches, France, 3University Hospital of North Staffordshire, Burslem, UK, 4Kliniken Beelit Gmbh, Beelitz, Germany, 5Ospedale dei bambini, Milano, Italy, 6LKH Hochzirl, Zirl, Austria, 7Medtronic International, Tolochenaz, Switzerland

   

ND2

MODELING THE COST-EFFECTIVENESS OF A NEW TREATMENT FOR MS (NATALIZUMAB) COMPARED TO CURRENT STANDARD PRACTICE IN SWEDEN

 

Kobelt G1, Berg J2, Lindgren P2, Hillert J3

 

1European Health Economics, Speracedes, France, 2i3 Innovus, Stockholm, Sweden, 3Karolinska Institute, Stockholm, Sweden

   

ND3

MODELING TREATING MULTIPLE SCLEROSIS WITH DISEASE MODIFYING DRUGS USING DISCRETE EVENT SIMULATION

 

Guo S1, Copur D1, Ward A1, Bennett R2, Al-Sabbah A2, Meletiche DM2, Caro JJ1

 

1Caro Research Institute, Concord, MA, USA, 2EMD Serono, Inc, Rockland, MA, USA

   

ND4

COST-EFFECTIVENESS OF A LIDOCAINE PLASTER RELATIVE TO PREGABALIN IN THE TREATMENT OF POST-HERPETIC NEURALGIA IN SCOTLAND

 

Dakin HA1, Nuijten MJC2, Poulsen Nautrup B3, Liedgens H3

 

1Abacus International, Bicester, Oxfordshire, UK, 2Erasmus University, Rotterdam, The Netherlands, 3Grünenthal GmbH, Aachen, Germany

 

 

Respiratory Disease

   

RS1

A RETROSPECTIVE, OBSERVATIONAL STUDY COMPARING OUTCOMES OF ASTHMA TREATMENT WITH FIXED COMBINATIONS OF INHALED CORTICOSTEROID AND LONG-ACTING â2-AGONIST (ICS/LABA) IN REAL-LIFE PRACTICE

 

Thomas M1, Von Ziegenweidt J2, Wirén A3, Ståhl E3, Price D1

 

1University of Aberdeen, Aberdeen, UK, 2Respiratory Research Ltd, Aberdeen, UK, 3AstraZeneca, Lund, Sweden

   

RS2

RESOURCE USE AND FINANCIAL IMPACT OF CRITICALLY ILL PATIENTS WITH PNEUMONIA AND RESPIRATORY FAILURE IN THE UNITED STATES

 

Mank J1, Chalfin DB2, Caeser M1

 

1ALTANA Pharma AG, Konstanz, Germany, 2Analytica International, Inc, New York, NY, USA

   

RS3

IMPACT OF SOCIO-ECONOMIC FACTORS ON PATIENTS' KNOWLEDGE OF THEIR CONDITION, INVOLVEMENT IN TREATMENT DECISIONS AND THE SUBSEQUENT COMPLIANCE WITH THEIR TREATMENT REGIMEN

 

Palm M1, Higgins V2, Lawson R1, Piercy J3

 

1Adelphi Group Products, Bollington, Cheshire, UK, 2Adelphi Group Products, New York, NY, USA, 3Adelphi Group, Bollington, UK

   

RS4

ASTHMA COSTS AND UTILIZATION IN A MANAGED CARE ORGANIZATION

 

Hay JW1, Zeiger RS2, Contreras RX3, Chen W3, Quinn VP3, Seal B4, Schatz MX2

 

1University of Southern California, Los Angeles, CA, USA, 2Kaiser Permanente Medical Center, San Diego, CA, USA, 3Kaiser Permanente Southern California Region, Pasadena, CA, USA, 4Sanofi-Aventis, Bridgewater, NJ, USA

   
  See all podium

 

 

16:45-17:00
Break, Exhibits & Contributed Poster Presentations – Session II Viewing
17:00-18:00
ISPOR Forums
ISPOR Transferability of Economic Data Task Force Forum

Monday 22 October 17:00 - 18:00

Speakers:  Michael Drummond PhD, Professor of Health Economics, University of York Centre for Health Economics, Heslington, York, UK;  Mark Sculpher PhD, MSc , Professor, University of York Centre for Health Economics, Heslington, York, UK;  Hans Severens PhD, Professor, MTA University of Maastrich, Department of Health Organization, Policy, and Economics, Maastricht, Netherlands

 This Task Force is now nearing completion of its draft report.  In addressing transferability issues, four situations have been considered: (i)where individual patient data on costs and outcomes are available, including the country of interest; (ii)where an economic study exists for another country and can potentially be transferred to the country of interest; (iii)where a new modeling study needs to be conducted for the country of interest and (iv)where the country of interest is a small country with no previous economic or clinical studies. In each case the interim recommendations of the Task Force will be presented and the main unresolved issues discussed.

 
ISPOR Health Technology Assessment (HTA) Special Interest Group Forum

Monday 22 October 17:00 - 18:00

HEALTH TECHNOLOGY ASSESSMENT (HTA) FORUM

European network for HTA (EUnetHTA) Draft Core HTA Model for Medical and Surgical Interventions & ISPOR Comments

EUnetHTA, supported by the European Union and EUnetHTA members, consists of partners from 27 European countries. The goal of EUnetHTA is to establish an effective and sustainable European network for HTA that informs policy decisions. Projects in development include practical tools to facilitate knowledge sharing between European HTA organizations, produce common core HTAs that can be shared, adapt existing HTAs from one country to other settings, address transferability of HTA to health policy issues, facilitate capacity building for HTA, monitor development of emerging new technologies, and prioritize topics for HTA. The draft Core HTA Model & an example of its use were recently released for comment. During this forum, the EUnetHTA draft core model (a tool for producing a common core of HTA evidence on clinical effectiveness, economic data social, cultural and ethical issues) & example of its use as well as ISPOR comments on this core model and example will be presented.

Moderator: Marilyn Dix Smith RPh, PhD, Executive Director, ISPOR, Lawrenceville, NJ, USA
Speakers: Finn Boerlum Kristensen MD, PhD, Danish Centre for HTA (DACHTA) Copenhagen, Denmark & Harri Sintonen PhD, Professor, Department of Public Health, University of Helsinki, Helsinki, Finland
Speaker: Leslie Levin MB, MD, FRCP, Medical Advisory Secretariat, Ontario Ministry of Health and Long Term Care, Toronto,  ON, Canada
Speaker: Vladimir Zah KS, ACIM, CPIAPD, ZRx Outcomes Research Inc., Toronto, ON, Canada
Speaker: Richard Willke PhD,  Senior Director, Global Outcome Research, Pfizer, Bridgewater, NJ USA

 
ISPOR Digest of International Databases

Monday 22 October 17:00-18:00

ISPOR Digest of International Databases Forum
This forum will present the ISPOR Digest of International Databases and will include an update, a review of the survey instrument (questionnaire form) and a summary of the database organizations surveyed thus far. The Digest includes 48 databases from 36 countries. An audience discussion will follow concerning the comprehensiveness of the Digest questionnaire form and to permit attendees to recommend other European database organizations to include in the Digest.  The Digest is an initiative of the ISPOR Retrospective Database SIG – Classification of Databases Working Group.

Speakers: Carl Asche PhD, Co-Chair, Classification of Databases Working Group and Associate Professor, University of Utah, Salt Lake City, Utah, USA; Gordon Cummins MS, Co-Chair, Classification of Databases Working Group and National Account Manager, Surveillance Data Inc., Farmington, MO, USA; Michael Johnson PhD, Co-Chair, Retrospective Database SIG and Associate Professor, University of Houston, College of Pharmacy, Houston, TX USA

 
Assessment, Determinants & Economics of Medication Compliance & Persistence: ISPOR Medication Compliance & Persistence SIG Forum

Monday 22 October 17:00-18:00

ASSESSMENT, DETERMINANTS & ECONOMICS OF MEDICATION COMPLIANCE & PERSISTENCE: ISPOR MEDICATION COMPLIANCE & PERSISTENCE SIG FORUM
Moderator: Dyfrig Hughes PhD, ISPOR Medication Compliance & Persistence SIG Chair & Senior Research Fellow in Pharmacoeconomics, University of Wales, Bangor, UK

 Key Considerations for Evaluation Prospective Research on Medication Compliance & Persistence
Critically appraising articles that involve compliance research requires an understanding about the best methodology to conduct trials within a number of study settings such as:  randomized controlled clinical trials setting, observational cohort, and quasi-experimental.  Key considerations for researchers regarding the design, analysis and reporting of results of such trials will be reviewed.
Speaker: Dyfrig Hughes, PhD, on behalf of the ISPOR Analyses Standards Working Group & Senior Research Fellow in Pharmacoeconomics, University of Wales, Bangor, UK

The Costs of Noncompliance
Medication non-compliance and failure to persist with chronic treatments have substantial economic consequences.  A systematic review of the literature will aim to provide the basis for a cost of ‘illness’ study for selected diseases.
Speaker: Rachel Elliott PhD, on behalf of the ISPOR Economics of Compliance & Persistence Working Group, Professor, University of Nottingham, UK

Determinants of Compliance & Persistence
Interventions aimed at improving compliance often are not adequately targeted at key "determinants".  A systematic approach to match interventions to selected populations will improve the likelihood of achieving a positive effect.
Speaker: Femida Gwadry-Sridhar PhD, RPh, MSc, ISPOR Determinants of Compliance & Persistence Working Group Chair & Assistant Professor, University of Western Ontario & Mc Master University, Director CCR-Net & Director LHR Institute, London, ON, Canada

 
ISPOR Central & Eastern European Forum

Monday 22 October 17:00-18:00

ISPOR Central and Eastern European Forum

DRUG POLICY AND PHARMACOECONOMICS WITHIN THE SLOVAK REPUBLIC
Speaker: Tomas Tesar, PharmD, PhD, Faculty of Pharmacy, Comenius University, Bratislava, Slovak Republic

THE CODE OF ETHICS OF THE ISPOR POLAND CHAPTER
Speaker: Tomasz Hermanowski, PhD, Professor, Technical University, Business School, Warsaw, Poland

REIMBURSEMENT ISSUES, PHARMACOECONOMIC METHODOLOGIES AND INTERNATIONAL SUMMER SCHOOL IN TURKEY
Speaker: Cankat Tulunay, MD, PhD, Professor, Medical School of Ankara University, Department of Clinical Pharmacology, Ankara, Turkey

THE EXECUTION OF PHARMACOECONOMICAL ANALYSES AND REIMBURSEMENT OF PHARMACEUTICALS IN CZECH REPUBLIC
Speaker: Tomas Dolezal, MD, PhD, 3rd Medical Faculty, Charles University, Prague, Czech Republic

The use of pharmacoeconomics in the process of updating the national list of health services in Israel
Speaker: Dan Greenberg, PhD, Department of Health Systems Management, Faculty of Health Sciences & Guilford Glazer School of Business and Management, Ben-Gurion University of the Negev, Beer-Sheva, Israel

18:00-19:00
ISPOR Forums - Russia Local Chapter (RSPOR) Forum
  Pharmacoeconomics and Influencing Decision Making in Preferred Drug List: ISPOR Russia Chapter Forum
 

MONDAY 22 OCTOBER 18:00-19:30

PHARMACOECONOMICS AND DECISION MAKING IN RUSSIAN REIMBURSEMENT: ISPOR RUSSIA LOCAL CHAPTER FORUM
Presented in Russian
Moderator: Pavel Vorobyev, MD, PhD, RSPOR President & Professor, Moscow Medical Academy named after Sechenov, Head of the Research Department on Problems of Standardization in Health Care, Moscow, Russia

Economics of standards of Health care in Russia
Speaker: Pavel Vorobyev, MD, PhD, Professor, RSPOR President, Moscow Medical Academy named after Sechenov, Head of the Research Department on Problems of Standardization in Health Care, Moscow, Russia

Economic principles of PHARMACEUTICAL drug selection  for reimbursement system IN THE RF
Speaker: Yury Belousov, MD, PhD, Professor, Corr-Member of RAMN, RSPOR Vice-President, Russian State Medical University, Head of Department of Clinical Pharmacology, Moscow, Russia

Role and purpose of pharmaceutical industry in provision of modern drugs
Speaker: Olga Mirolubova, PharmD, PhD, Russian Ministry of Industry and Energy, Department of Industry, Head of the Department of Industry Policy, Moscow, Russia

Main problems and advantages of therapeutic system management in Moscow
Speaker: Leonid Lazebnik, MD, PhD, Professor, Chief physician of Moscow Healthcare Department, Moscow, Russia

Experience of PHARMACEUTICAL drug SUPPLY AS The example of Saint-Petersburg
Speaker: Alla Rudakova, PhD, Executive Secretary of Formulary Committee of Main Military Medicine Department of Russian Ministry of Defense, Saint-Petersburg, Russia

Economics of new technologies: diagnostic methods and biologic medicines for target therapy
Speaker: Oleg Borisenko, MD, RSPOR Executive Director, Moscow, Russia

18:00-19:30
Exhibitors’ Wine & Cheese Reception & Poster Presentations – Session II
20:00-23:30
Social Event – ISPOR Rocks the Guinness Storehouse