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PHM1 |
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HEALTH-RELATED QUALITY OF
LIFE OF ANEMIA PATIENTS IN THE U.S.
Cremieux PY1, Xie J2, Wu EQ3, Castor AR1,
1Analysis Group Inc, Boston, MA, USA, 2The
University of North Carolina at Chapel Hill,
Chapel Hill, NC, USA, 3Analysis
Group, Boston, MA, USA
OBJECTIVE:
To assess the health-related quality of
life (HRQL) of anemia patients in the U.S.
METHODS:
SF-12 and EQ-5D results from adults (age
>= 18) in the 2000 and 2002 Medical Expenditure
Panel Survey (MEPS) were used in this study. The
anemia sample (i.e. patients with anemia, ICD9CM
280-285) was compared to a non-anemia sample (i.e.
people without anemia) using SF-12 physical and
mental scores and EQ-5d index scores. Differences
in HRQL scores between the anemia and non-anemia
samples were reported using absolute difference
and effect size (ES). Certain demographics (e.g.
age, sex, race, and geographic region) were
controlled for using stratification matching
methods. All analyses were adjusted to be
nationally representative. RESULTS:
A total of
39,735 adults were included in the study, of which
643 were reported to have anemia, corresponding to
1.42% of the adult U.S. population. The SF-12
physical scores, SF-12 mental scores, and EQ-5D
index scores of anemia patients were 1.87, 5.63,
and 0.10 lower than non-anemia people (1.87%,
5.63% and 10%; ES = 0.17, 0.45, and 0.32,
respectively). The differences in all three HRQL
scores are statistically significant (p<0.01)
after adjusting for age, sex, race, and geographic
location. CONLUSIONS:
Anemia is a serious
condition that significantly reduces patients’
physical and mental HRQL and overall health
utility in the U.S. |
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